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RM 2,650+ Direct flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — KUL
1 Sep — 8 Sep1
1 adult
1 adult, Economy, 0 bags

Find direct flights from Panama City within your budget

 
Use the slider to find direct flights from Panama City within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 407,431 searches. This data was last updated on 2 August 2026.

Fly to

Route

Departure

Return

Price

Cheapest return flight

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 11/10

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Mon 26/10

15:10-19:45

Nonstop10h 35m

RM 3,258

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 30/9

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Wed 14/10

15:05-18:40

Nonstop10h 35m

RM 3,311

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 19/10

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Wed 28/10

15:10-19:45

Nonstop10h 35m

RM 3,385

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 20/9

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Tue 13/10

15:05-18:40

Nonstop10h 35m

RM 3,385
Fastest return journey

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 27/10

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Wed 18/11

15:10-19:45

Nonstop10h 35m

RM 3,511

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Fri 18/9

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Sun 27/9

15:05-18:40

Nonstop10h 35m

RM 3,576

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 13/9

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Wed 30/9

15:05-18:40

Nonstop10h 35m

RM 3,585

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Fri 2/10

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Fri 16/10

15:05-18:40

Nonstop10h 35m

RM 3,707

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 15/9

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Sun 4/10

15:05-18:40

Nonstop10h 35m

RM 3,772

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Thu 1/10

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Thu 15/10

15:05-18:40

Nonstop10h 35m

RM 3,825

Flights are sorted by cheapest return flights first.

Deals found on 1/8

Showing 1-10 of 21 resultsSorted by cheapest first
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Best time to book a flight from Panama City

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Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

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