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RM 2,437+ Direct flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — KUL
18 Mar — 25 Mar1
1 adult
1 adult, Economy, 0 bags

Direct flights from Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 16 February 2026.

Wed 15/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Thu 30/415:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 12/2RM 2,632
Sun 19/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Sun 3/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 12/2RM 2,694
Mon 4/520:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Sat 9/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 13/2RM 2,734
Tue 31/320:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Tue 14/415:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 12/2RM 2,737
Mon 25/520:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Sat 30/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 13/2RM 2,796
Tue 28/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Sat 16/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 13/2RM 2,816
Wed 15/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Mon 27/415:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 14/2RM 2,819
Wed 27/520:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Thu 4/615:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 13/2RM 2,839
Wed 6/520:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Sun 10/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 13/2RM 2,858
Wed 15/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Sun 31/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 13/2RM 2,882
Wed 15/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Wed 3/615:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 13/2RM 2,921
Tue 19/520:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Sun 31/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 12/2RM 2,925

Find direct flights from Panama City within your budget

 
Use the slider to find direct flights from Panama City within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 407,431 searches. This data was last updated on 16 February 2026.

Fly to

Kuala Lumpur Intl

Route

Departure

Return

Price

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 4/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Wed 6/5

15:05-18:40

Nonstop10h 35m

RM 2,734

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 31/3

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Tue 14/4

15:05-18:40

Nonstop10h 35m

RM 2,737

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Thu 4/6

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Tue 9/6

15:05-18:40

Nonstop10h 35m

RM 2,839

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 24/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Thu 11/6

15:05-18:40

Nonstop10h 35m

RM 2,839

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 2/6

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Wed 17/6

15:05-18:40

Nonstop10h 35m

RM 2,839

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 18/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Fri 5/6

15:05-18:40

Nonstop10h 35m

RM 2,839

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 17/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Mon 1/6

15:05-18:40

Nonstop10h 35m

RM 2,839

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Thu 28/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Mon 8/6

15:05-18:40

Nonstop10h 35m

RM 2,839

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 3/6

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Thu 11/6

15:05-18:40

Nonstop10h 35m

RM 2,839

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 6/6

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Fri 12/6

15:05-18:40

Nonstop10h 35m

RM 2,839

Flights are sorted by cheapest return flights first.

Deals found on 14/2

Showing 1-10 of 20 results
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Estimated return price
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