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RM 2,526+ Direct flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — KUL
31 Jan — 7 Feb1
1 adult
1 adult, Economy, 0 bags

Direct flights from Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 1 January 2026.

Tue 10/321:30PTY - MAD
Nonstop9h 35mAir Europa
Sat 21/315:10MAD - PTY
Nonstop10h 35mAir Europa
Deal found 31/12RM 2,940
Mon 27/420:25PTY - MAD
Nonstop9h 50mAir Europa
Sun 17/515:05MAD - PTY
Nonstop10h 35mAir Europa
Deal found 30/12RM 2,944
Tue 28/420:25PTY - MAD
Nonstop9h 50mAir Europa
Sat 16/515:05MAD - PTY
Nonstop10h 35mAir Europa
Deal found 31/12RM 2,960
Fri 13/321:30PTY - MAD
Nonstop9h 35mAir Europa
Sun 15/315:10MAD - PTY
Nonstop10h 35mAir Europa
Deal found 31/12RM 3,069
Wed 4/321:30PTY - MAD
Nonstop9h 35mAir Europa
Sat 14/315:10MAD - PTY
Nonstop10h 35mAir Europa
Deal found 30/12RM 3,073
Tue 2/620:25PTY - MAD
Nonstop9h 50mAir Europa
Sat 22/815:05MAD - PTY
Nonstop10h 35mAir Europa
Deal found 1/1RM 3,195
Sun 15/221:30PTY - MAD
Nonstop9h 35mAir Europa
Tue 24/215:10MAD - PTY
Nonstop10h 35mAir Europa
Deal found 30/12RM 3,199
Thu 5/321:30PTY - MAD
Nonstop9h 35mAir Europa
Sun 8/315:10MAD - PTY
Nonstop10h 35mAir Europa
Deal found 31/12RM 3,329
Wed 11/221:30PTY - MAD
Nonstop9h 35mAir Europa
Fri 20/215:10MAD - PTY
Nonstop10h 35mAir Europa
Deal found 31/12RM 3,333
Tue 31/320:25PTY - MAD
Nonstop9h 50mAir Europa
Tue 14/415:05MAD - PTY
Nonstop10h 35mAir Europa
Deal found 1/1RM 3,349
Thu 12/221:30PTY - MAD
Nonstop9h 35mAir Europa
Wed 25/215:10MAD - PTY
Nonstop10h 35mAir Europa
Deal found 30/12RM 3,353

Find direct flights from Panama City within your budget

 
Use the slider to find direct flights from Panama City within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 407,431 searches. This data was last updated on 1 January 2026.

Fly to

Kuala Lumpur Intl

Route

Departure

Return

Price

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 8/3

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Sun 15/3

15:10-19:45

Nonstop10h 35m

RM 2,940

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 11/3

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Sun 15/3

15:10-19:45

Nonstop10h 35m

RM 2,940

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 10/3

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Thu 19/3

15:10-19:45

Nonstop10h 35m

RM 2,940

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 9/3

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Wed 18/3

15:10-19:45

Nonstop10h 35m

RM 2,940

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 9/3

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Fri 20/3

15:10-19:45

Nonstop10h 35m

RM 2,940

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 10/3

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Sun 15/3

15:10-19:45

Nonstop10h 35m

RM 2,940

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Fri 13/3

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Tue 17/3

15:10-19:45

Nonstop10h 35m

RM 3,069

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 27/4

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Sat 20/6

15:05-18:40

Nonstop10h 35m

RM 3,069

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 15/4

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Thu 30/4

15:05-18:40

Nonstop10h 35m

RM 3,069

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 9/2

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Wed 25/2

15:10-19:45

Nonstop10h 35m

RM 3,069

Flights are sorted by cheapest return flights first.

Deals found on 1/1

Showing 1-10 of 21 results
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Estimated return price
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