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RM 2,438+ Direct flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 18/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — KUL
4 Mar — 11 Mar1
1 adult
1 adult, Economy, 0 bags

Direct flights from Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 2 February 2026.

Mon 27/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Sun 17/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 1/2RM 2,856
Wed 22/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Wed 29/415:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 2/2RM 2,864
Thu 21/520:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Thu 20/815:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 1/2RM 2,966
Wed 18/221:30
PTY
-
MAD
Nonstop9h 35m
Air Europa
Mon 16/315:10
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 1/2RM 2,994
Wed 4/321:30
PTY
-
MAD
Nonstop9h 35m
Air Europa
Sat 14/315:10
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 2/2RM 3,092
Wed 4/321:30
PTY
-
MAD
Nonstop9h 35m
Air Europa
Thu 19/315:10
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 1/2RM 3,120
Fri 8/521:30
PTY
-
MAD
Nonstop9h 50m
Iberia
Sun 24/515:55
MAD
-
PTY
Nonstop11h 05m
Iberia
Deal found 1/2RM 3,163
Tue 19/520:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Wed 19/815:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 1/2RM 3,218
Thu 5/321:30
PTY
-
MAD
Nonstop9h 35m
Air Europa
Sun 8/315:10
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 31/1RM 3,238
Wed 4/321:30
PTY
-
MAD
Nonstop9h 35m
Air Europa
Wed 1/415:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 1/2RM 3,246
Tue 3/321:30
PTY
-
MAD
Nonstop9h 35m
Air Europa
Tue 17/315:10
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 1/2RM 3,265
Mon 2/321:30
PTY
-
MAD
Nonstop9h 35m
Air Europa
Wed 1/415:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 1/2RM 3,392

Find direct flights from Panama City within your budget

 
Use the slider to find direct flights from Panama City within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 407,431 searches. This data was last updated on 2 February 2026.

Fly to

Kuala Lumpur Intl

Route

Departure

Return

Price

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 28/4

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Sat 16/5

15:05-18:40

Nonstop10h 35m

RM 2,856

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 17/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Sat 6/6

15:05-18:40

Nonstop10h 35m

RM 2,864

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 17/2

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Thu 19/3

15:10-19:45

Nonstop10h 35m

RM 2,994

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Thu 2/4

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Wed 22/4

15:05-18:40

Nonstop10h 35m

RM 2,994

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 4/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Sun 17/5

15:05-18:40

Nonstop10h 35m

RM 2,994

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 4/3

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Sat 14/3

15:10-19:45

Nonstop10h 35m

RM 3,092

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Thu 19/2

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Sat 14/3

15:10-19:45

Nonstop10h 35m

RM 3,120

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 4/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Wed 6/5

15:05-18:40

Nonstop10h 35m

RM 3,120

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Thu 19/2

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Fri 13/3

15:10-19:45

Nonstop10h 35m

RM 3,120

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 5/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Sun 17/5

15:05-18:40

Nonstop10h 35m

RM 3,120

Flights are sorted by cheapest return flights first.

Deals found on 2/2

Showing 1-10 of 20 results
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Estimated return price
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