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RM 2,431+ Direct flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — KUL
23 Mar — 30 Mar1
1 adult
1 adult, Economy, 0 bags

Direct flights from Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 21 February 2026.

Wed 29/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Thu 21/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 19/2RM 2,626
Mon 20/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Wed 6/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 17/2RM 2,688
Sat 18/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Mon 27/415:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 20/2RM 2,692
Tue 31/320:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Tue 14/415:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 20/2RM 2,724
Mon 11/520:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Fri 22/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 18/2RM 2,731
Wed 22/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Sat 30/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 19/2RM 2,755
Mon 11/520:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Sun 24/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 18/2RM 2,794
Tue 28/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Sat 16/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 20/2RM 2,806
Fri 24/420:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Tue 5/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 17/2RM 2,817
Mon 11/520:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Mon 1/615:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 18/2RM 2,837
Mon 4/520:25
PTY
-
MAD
Nonstop9h 50m
Air Europa
Wed 6/515:05
MAD
-
PTY
Nonstop10h 35m
Air Europa
Deal found 19/2RM 2,856

Find direct flights from Panama City within your budget

 
Use the slider to find direct flights from Panama City within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 407,431 searches. This data was last updated on 21 February 2026.

Fly to

Kuala Lumpur Intl

Route

Departure

Return

Price

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 29/4

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Mon 25/5

15:05-18:40

Nonstop10h 35m

RM 2,626

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 18/4

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Wed 29/4

15:05-18:40

Nonstop10h 35m

RM 2,692

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 18/4

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Mon 27/4

15:05-18:40

Nonstop10h 35m

RM 2,692

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 29/4

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Sun 24/5

15:05-18:40

Nonstop10h 35m

RM 2,692

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 29/4

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Sat 23/5

15:05-18:40

Nonstop10h 35m

RM 2,692

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 31/3

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Tue 14/4

15:05-18:40

Nonstop10h 35m

RM 2,731

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 17/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Wed 27/5

15:05-18:40

Nonstop10h 35m

RM 2,731

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 11/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Fri 22/5

15:05-18:40

Nonstop10h 35m

RM 2,731

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 19/4

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Sat 25/4

15:05-18:40

Nonstop10h 35m

RM 2,817

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 28/4

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Wed 20/5

15:05-18:40

Nonstop10h 35m

RM 2,817

Flights are sorted by cheapest return flights first.

Deals found on 17/2

Showing 1-10 of 23 results
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Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

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