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RM 1,461+ Direct flights from Santo Domingo

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
SDQ — BCN
14 Dec — 21 Dec1
1 adult
1 adult, Economy, 0 bags

Direct flights from Santo Domingo

Enter your travel dates to find the best prices.

Cheapest flights from Santo Domingo
Explore the most affordable flight options available from Santo Domingo. Find the lowest fares based on data from user searches, with prices last updated on 14 November 2025.

Tue 23/1222:50SDQ - MAD
Nonstop8h 05mAir Europa
Sat 24/116:15MAD - SDQ
Nonstop9h 00mAir Europa
Deal found 13/11RM 2,740
Thu 12/223:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Sun 22/216:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 12/11RM 2,778
Thu 12/223:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Thu 5/316:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 12/11RM 2,938
Sun 1/323:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Thu 12/316:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 13/11RM 2,959
Sat 20/1223:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Sun 11/116:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 13/11RM 2,963
Mon 22/1222:50SDQ - MAD
Nonstop8h 05mAir Europa
Tue 13/111:30MAD - SDQ
Nonstop9h 00mAir Europa
Deal found 13/11RM 2,976
Sun 1/323:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Sun 15/316:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 13/11RM 3,124
Sun 29/321:10SDQ - MAD
Nonstop8h 20mWorld2Fly
Thu 9/414:45MAD - SDQ
Nonstop8h 55mWorld2Fly
Deal found 12/11RM 3,137
Sun 28/1223:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Sat 24/116:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 13/11RM 3,145
Sat 20/1222:50SDQ - MAD
Nonstop8h 05mAir Europa
Mon 5/111:30MAD - SDQ
Nonstop9h 00mAir Europa
Deal found 12/11RM 3,223

Find direct flights from Santo Domingo within your budget

 
Use the slider to find direct flights from Santo Domingo within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 407,431 searches. This data was last updated on 14 November 2025.

Fly to

Barcelona-El Prat

Route

Departure

Return

Price

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Tue 23/12

22:50-11:55

Nonstop8h 05m

Madrid Barajas

Sat 24/1

16:15-20:15

Nonstop9h 00m

RM 2,740

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Sun 15/2

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Sun 22/3

16:20-20:35

Nonstop9h 15m

RM 2,778

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Thu 12/2

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Thu 5/3

16:20-20:35

Nonstop9h 15m

RM 2,938

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Thu 7/5

21:10-11:30

Nonstop8h 20m

Madrid Barajas

Thu 14/5

14:45-17:40

Nonstop8h 55m

RM 3,124

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Sun 1/3

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Sun 15/3

16:20-20:35

Nonstop9h 15m

RM 3,124

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Sat 27/12

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Sun 11/1

16:20-20:35

Nonstop9h 15m

RM 3,322

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Tue 23/12

21:45-11:00

Nonstop8h 15m

Madrid Barajas

Wed 21/1

15:55-20:10

Nonstop9h 15m

RM 3,335

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Fri 12/12

22:00-11:30

Nonstop8h 30m

Madrid Barajas

Mon 12/1

15:55-20:10

Nonstop9h 15m

RM 3,392

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Sun 21/12

21:45-11:00

Nonstop8h 15m

Madrid Barajas

Mon 12/1

11:55-16:15

Nonstop9h 20m

RM 3,392

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Fri 19/12

21:45-11:00

Nonstop8h 15m

Madrid Barajas

Thu 8/1

11:55-16:15

Nonstop9h 20m

RM 3,450

Flights are sorted by cheapest return flights first.

Deals found on 13/11

Showing 1-10 of 18 results
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Best time to book a flight from Santo Domingo

Have a flexible travel schedule? Discover the best time to fly from Santo Domingo with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Access useful and relevant information related to your journey from Santo Domingo. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 14 November 2025.

  • Where can you fly direct from Santo Domingo?

    Currently, the most popular direct flight destination from Santo Domingo is New York John F Kennedy Intl Airport.

  • What is the best time of year to fly direct from Santo Domingo?

    If you're seeking the lowest price on a direct flight from Santo Domingo, October is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, January offers travelers the most options.

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