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RM 1,499+ Direct flights from Santo Domingo

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 22/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
SDQ — BCN
13 Nov — 20 Nov1
1 adult
1 adult, Economy

Direct flights from Santo Domingo

Enter your travel dates to find the best prices.

Cheapest flights from Santo Domingo
Explore the most affordable flight options available from Santo Domingo. Find the lowest fares based on data from user searches, with prices last updated on 14 October 2025.

Sun 26/1023:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Thu 30/1016:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 13/10RM 2,957
Sun 26/1023:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Thu 13/1116:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 13/10RM 2,999
Sun 21/1223:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Sat 3/116:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 12/10RM 3,007
Sun 16/1123:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Thu 20/1116:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 13/10RM 3,011
Sun 2/1123:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Thu 1/116:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 13/10RM 3,045
Thu 20/1123:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Sun 8/216:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 13/10RM 3,054
Thu 6/1123:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Thu 20/1116:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 12/10RM 3,189
Sun 15/323:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Thu 26/316:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 13/10RM 3,231
Thu 26/323:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Thu 23/414:45MAD - SDQ
Nonstop8h 55mWorld2Fly
Deal found 13/10RM 3,235
Thu 12/223:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Sun 22/216:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 14/10RM 3,273
Thu 13/1123:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Thu 27/1116:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 12/10RM 3,282
Thu 20/1123:05SDQ - MAD
Nonstop8h 20mWorld2Fly
Thu 27/1116:20MAD - SDQ
Nonstop9h 15mWorld2Fly
Deal found 13/10RM 3,286

Find direct flights from Santo Domingo within your budget

 
Use the slider to find direct flights from Santo Domingo within your budget. Price data is based on user searches made on Cheapflights. Over the past seven days, Cheapflights users made 407,431 searches. This data was last updated on 14 October 2025.

Fly to

Barcelona-El Prat

Route

Departure

Return

Price

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Sun 26/10

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Thu 30/10

16:20-20:35

Nonstop9h 15m

RM 2,957

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Sun 21/12

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Sat 3/1

16:20-20:35

Nonstop9h 15m

RM 3,007

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Sun 16/11

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Thu 20/11

16:20-20:35

Nonstop9h 15m

RM 3,011

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Sat 20/12

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Sat 10/1

16:20-20:35

Nonstop9h 15m

RM 3,011

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Thu 6/11

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Thu 20/11

16:20-20:35

Nonstop9h 15m

RM 3,045

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Thu 20/11

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Sun 8/2

16:20-20:35

Nonstop9h 15m

RM 3,054

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Sun 15/3

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Thu 26/3

16:20-20:35

Nonstop9h 15m

RM 3,231

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Sun 1/3

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Thu 12/3

16:20-20:35

Nonstop9h 15m

RM 3,273

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Sun 23/11

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Thu 27/11

16:20-20:35

Nonstop9h 15m

RM 3,286

Santo DomingoMadrid

SDQ - MAD

SDQMAD

Santo Domingo Las Americas

Thu 11/12

23:05-12:25

Nonstop8h 20m

Madrid Barajas

Sun 4/1

16:20-20:35

Nonstop9h 15m

RM 3,320

Flights are sorted by cheapest return flights first.

Deals found on 12/10

Showing 1-10 of 19 results
1
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Best time to book a flight from Santo Domingo

Have a flexible travel schedule? Discover the best time to fly from Santo Domingo with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Access useful and relevant information related to your journey from Santo Domingo. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 14 October 2025.

  • Where can you fly direct from Santo Domingo?

    Currently, the most popular direct flight destination from Santo Domingo is New York John F Kennedy Intl Airport.

  • What is the best time of year to fly direct from Santo Domingo?

    If you're seeking the lowest price on a direct flight from Santo Domingo, October is worth consideration as prices are at their lowest, on average. In terms of the number of daily non-stop flights, January offers travelers the most options.

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