RM 2,320+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 16/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — KUL
11 Jan — 18 Jan1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 12 December 2025.

Good round-trip deal

RM 20,422 or less
Price to beat on a round-trip flight from Panama City Tocumen Intl.
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Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 12 December 2025.

Wed 4/222:05PTY - MAD
1 stop19h 20mMultiple Airlines
Wed 18/206:00MAD - PTY
1 stop20h 10mMultiple Airlines
Deal found 11/12RM 2,953
Mon 9/221:30PTY - MAD
Nonstop9h 35mAir Europa
Sun 8/315:10MAD - PTY
Nonstop10h 35mAir Europa
Deal found 10/12RM 2,977
Wed 15/420:25PTY - MAD
Nonstop9h 50mAir Europa
Thu 30/415:05MAD - PTY
Nonstop10h 35mAir Europa
Deal found 11/12RM 2,982
Mon 2/218:45PTY - MAD
1 stop33h 30mMultiple Airlines
Mon 16/206:00MAD - PTY
1 stop20h 10mMultiple Airlines
Deal found 11/12RM 2,998
Thu 25/1218:45PTY - MAD
1 stop36h 55mMultiple Airlines
Wed 21/106:00MAD - PTY
1 stop20h 10mMultiple Airlines
Deal found 10/12RM 3,002
Thu 25/1218:45PTY - MAD
1 stop36h 55mMultiple Airlines
Mon 19/118:45MAD - PTY
1 stop31h 25mMultiple Airlines
Deal found 11/12RM 3,010
Sun 8/218:45PTY - MAD
1 stop22h 40mMultiple Airlines
Sun 8/306:00MAD - PTY
1 stop20h 10mMultiple Airlines
Deal found 10/12RM 3,019
Sat 27/1218:45PTY - MAD
1 stop36h 55mMultiple Airlines
Tue 10/206:00MAD - PTY
1 stop20h 10mMultiple Airlines
Deal found 11/12RM 3,068
Wed 4/222:05PTY - MAD
1 stop30h 10mKLM
Sat 21/207:05MAD - PTY
1 stop18h 50mKLM
Deal found 11/12RM 3,072
Sun 8/218:45PTY - BCN
1 stop22h 20mKLM
Sun 22/219:55BCN - PTY
1 stop30h 00mKLM
Deal found 11/12RM 3,134
Sat 6/618:50PTY - BCN
1 stop20h 55mKLM
Sun 14/606:20BCN - PTY
1 stop17h 30mKLM
Deal found 10/12RM 3,146
Sun 8/218:45PTY - BCN
1 stop22h 20mMultiple Airlines
Sun 22/216:00BCN - PTY
1 stop34h 10mMultiple Airlines
Deal found 10/12RM 3,216

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 12 December 2025. In the last 7 days, Cheapflights users made a total of 407,431 searches

Fly to

Kuala Lumpur Intl

Route

Departure

Return

Price

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 15/2

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Wed 4/3

15:10-19:45

Nonstop10h 35m

RM 2,977

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 18/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Thu 21/5

15:05-18:40

Nonstop10h 35m

RM 2,977

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 9/2

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Thu 5/3

15:10-19:45

Nonstop10h 35m

RM 2,977

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 15/4

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Thu 30/4

15:05-18:40

Nonstop10h 35m

RM 2,977

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 8/2

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Thu 12/3

15:10-19:45

Nonstop10h 35m

RM 2,977

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 8/2

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Wed 11/3

15:10-19:45

Nonstop10h 35m

RM 2,977

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 9/2

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Wed 4/3

15:10-19:45

Nonstop10h 35m

RM 2,977

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 2/2

18:45-10:15

1 stop33h 30m

Madrid Barajas

Mon 16/2

06:00-20:10

1 stop20h 10m

RM 2,998

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 10/2

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Wed 4/3

15:10-19:45

Nonstop10h 35m

RM 3,109

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 30/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Sat 6/6

15:05-18:40

Nonstop10h 35m

RM 3,109

Flights are sorted by cheapest return flights first.

Deals found on 11/12

Showing 1-10 of 56 results
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Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City?

Currently, October is the cheapest month in which you can book a flight from Panama City (average of RM 4,029). Flying from Panama City in December will prove the most costly (average of RM 8,575). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

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Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 12 December 2025.

  • What are the most popular destinations to fly to from Panama City?

    This month, the top selected destinations from Panama City are Bogotá, Cali, Barranquilla. Throughout the year, Bogotá, Cancún, Cartagena are some of the top choices made by users flying from Panama City.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as RM 20,422 to Istanbul Airport (prices may vary depending on the airline and departure time). On average, users have booked flights for RM 20,886 to fly from Panama City.

  • What is the cheapest premium economy flight from Panama City?

    Options for some of the cheapest premium economy flights from Panama City we have found on Cheapflights are as follows:
    Panama City Tocumen Intl to Paris Charles de Gaulle Airport from RM 7,089

  • What is the cheapest month to fly from Panama City?

    Currently, the cheapest month for flights from Panama City is October. The most expensive month for flights is December. The cheapest prices are shown above but prices will vary according to departure times, airlines, class and how early you book.

  • How does Cheapflights help users find flights from Panama City?

    When you search for this flight from Panama City, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

  • Can Cheapflights find flights from Panama City with no change fees?

    Yes! Cheapflights helps users easily find flights from Panama City with no change fees.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes! Start tracking prices for flights from Panama City today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive the alerts.

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How does Cheapflights help users find flights from Panama City?

When you search for this flight from Panama City, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Panama City with no change fees?

Yes! Cheapflights helps users easily find flights from Panama City with no change fees.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes! Start tracking prices for flights from Panama City today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive the alerts.

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