RM 2,190+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — KUL
27 Feb — 6 Mar1
1 adult
1 adult, Economy, 0 bags

What to know about flights from Panama City

Discover essential information about flights departing from Panama City, including flight schedules, destinations, airlines operating at the Panama City airport, and any specific guidelines or requirements for travellers. Please note that the information is based on the most recent updates available. Data last updated 28 January 2026.

Good round-trip deal

RM 19,655 or less
Price to beat on a round-trip flight from Panama City Tocumen Intl.
Search Deals

Find flights from Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on 28 January 2026.

Sun 10/521:30
PTY
-
MAD
Nonstop9h 50m
Iberia
Fri 22/515:55
MAD
-
PTY
Nonstop11h 05m
Iberia
Deal found 26/1RM 2,613
Mon 1/618:50
PTY
-
MAD
1 stop31h 40m
Multiple Airlines
Wed 10/616:40
MAD
-
PTY
1 stop34h 05m
Multiple Airlines
Deal found 26/1RM 2,629
Fri 1/521:30
PTY
-
MAD
Nonstop9h 50m
Iberia
Sun 31/515:55
MAD
-
PTY
Nonstop11h 05m
Iberia
Deal found 26/1RM 2,656
Mon 15/618:50
PTY
-
MAD
1 stop14h 35m
Multiple Airlines
Mon 22/612:20
MAD
-
PTY
1 stop14h 25m
Multiple Airlines
Deal found 26/1RM 2,664
Mon 25/518:50
PTY
-
MAD
1 stop31h 40m
Multiple Airlines
Mon 15/612:20
MAD
-
PTY
1 stop14h 25m
Multiple Airlines
Deal found 25/1RM 2,704
Mon 9/218:45
PTY
-
MAD
1 stop33h 30m
KLM
Mon 23/220:30
MAD
-
PTY
1 stop26h 00m
KLM
Deal found 26/1RM 2,715
Sun 10/521:30
PTY
-
BCN
1 stop13h 40m
Iberia
Sun 17/507:00
BCN
-
PTY
1 stop20h 00m
Iberia
Deal found 26/1RM 2,719
Mon 8/618:50
PTY
-
MAD
1 stop21h 35m
Multiple Airlines
Fri 12/612:20
MAD
-
PTY
1 stop14h 25m
Multiple Airlines
Deal found 26/1RM 2,727
Mon 25/518:50
PTY
-
MAD
1 stop31h 40m
Multiple Airlines
Sat 13/620:15
MAD
-
PTY
1 stop30h 30m
Multiple Airlines
Deal found 25/1RM 2,755
Wed 27/521:30
PTY
-
MAD
Nonstop9h 50m
Iberia
Wed 17/615:55
MAD
-
PTY
Nonstop10h 40m
Iberia
Deal found 26/1RM 2,759
Wed 11/321:45
PTY
-
MAD
1 stop30h 40m
Turkish Airlines
Tue 17/317:55
MAD
-
PTY
1 stop31h 55m
Turkish Airlines
Deal found 27/1RM 2,763
Mon 16/221:45
PTY
-
BCN
1 stop37h 20m
Turkish Airlines
Sun 7/612:10
BCN
-
PTY
1 stop39h 15m
Turkish Airlines
Deal found 26/1RM 2,767

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on 28 January 2026. In the last 7 days, Cheapflights users made a total of 407,431 searches

Fly to

Kuala Lumpur Intl

Route

Departure

Return

Price

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 29/4

22:20-16:55

1 stop35h 35m

Madrid Barajas

Sun 17/5

12:00-20:25

1 stop39h 25m

RM 2,763

Panama CityBarcelona

PTY - BCN

PTYBCN

Panama City Tocumen Intl

Wed 22/4

22:20-17:40

1 stop36h 20m

Barcelona-El Prat

Mon 4/5

07:35-20:25

1 stop19h 50m

RM 2,767

Panama CityBarcelona

PTY - BCN

PTYBCN

Panama City Tocumen Intl

Mon 9/2

18:45-23:05

1 stop22h 20m

Barcelona-El Prat

Wed 18/2

06:00-16:30

1 stop16h 30m

RM 2,830

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 27/5

20:25-13:15

Nonstop9h 50m

Madrid Barajas

Thu 11/6

15:05-18:40

Nonstop10h 35m

RM 2,846

Panama CityBarcelona

PTY - BCN

PTYBCN

Panama City Tocumen Intl

Wed 8/4

22:20-23:20

1 stop18h 00m

Barcelona-El Prat

Wed 29/4

12:10-18:30

2 stops37h 20m

RM 2,850

Panama CityBarcelona

PTY - BCN

PTYBCN

Panama City Tocumen Intl

Wed 1/4

22:20-10:45

1 stop29h 25m

Barcelona-El Prat

Sun 19/4

19:05-20:25

1 stop32h 20m

RM 2,854

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 27/4

22:20-13:35

1 stop32h 15m

Madrid Barajas

Mon 11/5

18:25-18:25

2 stops31h 00m

RM 2,862

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 12/4

21:30-14:20

Nonstop9h 50m

Madrid Barajas

Sat 31/10

15:55-21:00

Nonstop11h 05m

RM 2,866

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 25/2

21:30-13:05

Nonstop9h 35m

Madrid Barajas

Sat 14/3

15:10-19:45

Nonstop10h 35m

RM 2,866

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 16/2

22:05-10:15

1 stop30h 10m

Madrid Barajas

Mon 23/2

16:50-16:30

1 stop29h 40m

RM 2,921

Flights are sorted by cheapest return flights first.

Deals found on 27/1

Showing 1-10 of 52 results
1
2
3
...
6

Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated return price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City?

Currently, October is the cheapest month in which you can book a flight from Panama City (average of RM 3,767). Flying from Panama City in December will prove the most costly (average of RM 8,253). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Direct flights from Panama

Book a direct flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated 28 January 2026.

  • What are the most popular destinations to fly to from Panama City?

    This month, the top selected destinations from Panama City are Bogotá, Cancún, David. Throughout the year, Bogotá, Cancún, Cartagena are some of the top choices made by users flying from Panama City.

  • What is the cheapest flight from Panama City to anywhere?

    Users have flown out of Panama City for as low as RM 19,655 to Istanbul Airport (prices may vary depending on the airline and departure time). On average, users have booked flights for RM 20,102 to fly from Panama City.

  • What is the cheapest month to fly from Panama City?

    Currently, the cheapest month for flights from Panama City is October. The most expensive month for flights is December. The cheapest prices are shown above but prices will vary according to departure times, airlines, class and how early you book.

  • How does Cheapflights help users find flights from Panama City?

    When you search for this flight from Panama City, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

  • Can Cheapflights find flights from Panama City with no change fees?

    Yes! Cheapflights helps users easily find flights from Panama City with no change fees.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes! Start tracking prices for flights from Panama City today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive the alerts.

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travellers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City?

When you search for this flight from Panama City, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the best flight for you.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Panama City for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Panama City with no change fees?

Yes! Cheapflights helps users easily find flights from Panama City with no change fees.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes! Start tracking prices for flights from Panama City today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive the alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book With Flexibility

Our users can plan ahead with confidence and find flights with no change fees.

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.