Cheap flights from Des Moines to anywhere

We've found St. Louis, Minneapolis, and Chicago as options for shorter direct flights within 375 km of Des Moines. These locations can be great options for travelers looking to go somewhere and back quickly.

We've found Santa Ana, Phoenix, and Portland as options for distant non-stop flights from Des Moines. Select dates and check pricing for the destination that meets your needs.

Some of the most frequent flights departing from Des Moines everyday are: Chicago (376 flights per day), Detroit (122 flights per day), and Atlanta (91 flights per day).

This month, the top selected destinations from Des Moines are Denver, Nashville, Dallas/Fort Worth Airport. Throughout the year, Denver, Nashville, Cancún are some of the top choices made by users flying from Des Moines.

Those who are seeking the cheapest fare on flights departing from Des Moines would be wise to consider leaving during Tuesday mornings when prices are typically at their lowest. When considering other options, price-conscious travelers should avoid Tuesday mornings when fares are usually the most expensive.

Deals for flights from Des Moines are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose to your preference, such as price, airport, cabin class, and plenty of other options.

Cheapflights helps you find that perfect flight from Des Moines by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Yes, we can. To see specific flights from Des Moines with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Yes, Cheapflights offers price alerts on flights from Des Moines so you can book your travels when it’s right. The Price Alerts feature is available by clicking the bell icon next to the flight deals above and providing your email address.